NRG1
2022-12-08:
NRG1 (Neuregulin 1) #
- There is NRG-1 through 4, and NRG-1 types I-VI. Neuregulin contains an EGF-like domain.
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Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system
- Its downregulation produces a disruption in glutamatergic signaling, and this is seen in schizophrenia.