Lactobacillus

2023-04-04:

Lactobacillus #

It’s even Peaty https://raypeatforum.com/community/threads/lactobacillus-pl-increases-endurance-subjects-by-58-percent.31589/
Lactobacillus reuteri: A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity - https://raypeatforum.com/community/threads/a-common-probiotic-strain-lactobacillus-may-cause-lupus.27085/
So why would you ever want more lactic acid? I guess lowering pH is an advantage; beneficial bacteria also thrive therein - supposedly

Swiss chad post: https://www.reddit.com/r/NooTopics/comments/12qj0rv/probiotics_for_athletic_performance/
- [Lactobacillus salivarius Subspecies salicinius SA-03 is a New Probiotic Capable of Enhancing Exercise Performance and Decreasing Fatigu]
  - Significantly improved muscle strength and endurance performance, increased hepatic and muscular glycogen storage, and decreased lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise.
- Supplementation with Human-Origin Probiotic Lactobacillus plantarum PL-02 Could Effectively Improve Muscle Mass and Exercise Performance, and Have an Anti-Fatigue Effect
  - could significantly increase muscle mass, improve muscle strength and endurance performance, and increase hepatic and muscular glycogen storage. Furthermore, PL-02 could significantly decrease fatigue biochemical parameters, such as lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels, after exercise.
- [Live and Heat-Killed Probiotic Lactobacillus paracasei PS23 Accelerated the Improvement and Recovery of Strength and Damage Biomarkers after Exercise-Induced Muscle Damage]
  - we found that L-PS23 or HK-PS23 supplementation for six weeks prevented strength loss after muscle damage and improved blood muscle damage and inflammatory markers, with protective, accelerated recovery and anti-fatigue benefits.
- Effects of Lactobacillus gasseri OLL2809 and α-lactalbumin on university-student athletes: a randomized, double-blind, placebo-controlled clinical trial
  - ingestion was effective in preventing reduced natural killer cell activity due to strenuous exercise and elevating mood from a depressed state. In addition, LG2809 + αLA was found to alleviate minor resting fatigue, which was supported objectively by the significant reduction in the serum reactive oxygen metabolites and transforming growth factor β1 levels

TWK-10 #

*Homofermentative, vancomycin resistant organisms with a nomadic lifestyle that ferment a wide range of carbohydrates; most species metabolise phenolic acids by esterase, decarboxylase and reductase activities. L. plantarum expresses pseudocatalase and nitrate reductase activities. *
They can respire oxygen and express cytochromes if heme and menaquinone are present in the growth medium. In the absence of heme and menaquinone, oxygen is consumed by NADH-peroxidase with hydrogen peroxide as intermediate and water as end product
In place of the protective enzyme superoxide dismutase present in almost all other oxygen-tolerant cells, this organism accumulates millimolar quantities of manganese polyphosphate. Manganese is also used by L. plantarum in a pseudo-catalase to lower reactive oxygen levels. Because the chemistry by which manganese complexes protect the cells from oxygen damage is subverted by iron, these cells contain virtually no iron atoms
L. Plantarum produces both L- and D-lactate. Cue: https://raypeatforum.com/community/threads/probiotics-are-dangerous-should-be-regulated-as-drugs.25418/
- Haidut says it’s okay if it’s in the gut, but small intestine = SIBO and should be sterile, and ideally the Colon as well.
  - I believe L. Plantarum does indeed survive in the GI tract

Human study: TWK10 increases endurance subjects by 58 percent
- Effect of Lactobacillus Plantarum TWK10 on Improving Endurance Performance in Humans
  - Healthy men. 1x100B CFU after each meal for 6 weeks.
    - 10 mothafuckin capsules!
  - No effect on post-workout lactate, ammonia, or creatine kinase. Higher post-workout glucose.
https://www.ergo-log.com/lactobacillus-plantarum-twk10.html
Feed it food with fructo-oligosaccharide prebiotics. NOW brand. I think this is also in breast milk prebiotic fiber.
- Cue the couple hits in this 980-post megathread: Why Is There So Much Soluble Fibre In Human Breast Milk
- Amazoniac has some good posts on this.
  - Microbial degradation of complex carbohydrates in the gut
    - The health benefits attributed to various prebiotics, including FOS and GOS, have been extensively reviewed:
Anywhere from 1-9 whole capsules ($30 90ct, 10B each): https://www.kaged.com/products/pro-biotic?variant=39367543652417 also sold on iherb. Quite possibly some bad quality control
Effect of Lactobacillus plantarum TWK10 on Exercise Physiological Adaptation, Performance, and Body Composition in Healthy Humans

PS128 #

Bifidobacterium longum OLP-01 #

Not even Lactobacillus but fuck it since this is the TWK10 page.

https://ergo-log.com/super-saiyan-probiotic-bifidobacterium-longum-olp-01.html
- Had smaller fat stores in the testicles, tf?

Dose #

So 3x/daily showed notable gains over 1x. It would make sense to honestly do a megadose at least for a loading period to actually estbalish the strain in your gut, and provide fructo-oligosaccharides all the while, and thereafter to sustain the population indefinitely (theoretically).

yana-notes