IKK

2022-08-25: reference:

IKK (IκB Kinase) #

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  • (Uses ATP) IκBα is an inhibitor of NF-κB when bound, whereby phosphorylation dissociates them allowing NF-κB to impart expression, and then IκB is ubiquinated.
  • The inflammatory activation of IKK is ultimately dependent on activation of IKKK: