yana-notes

Granule Cell

2022-04-30: reference:

Granule Cell 250 (B) #

Characterized by just having a few dendrites and one axon, called the Mossy Fiber.

  • Found in:
    • The cerebellar cotex’s granular layer
      • Input from Mossy Fibers (of the pontine nuclei/pons). Projects through the Purkinje layer into the molecular layer, then connects to dendrites of Purkinje Cell, forming the image shown above depicting ‘Gcpc synapses’.
        • It requires input from many mossy fibers, which receive much more gross sensory input.
      • Glutamatergic. Excites purkinje cells, but also inhibits them by exciting GABAergic interneurons.
    • Dentate Gyrus
    • Olfactory Bulb
      • GABAergic, axonless.
    • Cerebral Cortex.