Entorhinal Cortex
2022-04-26: Neuroanatomy reference:
Entorhinal Cortex #
- The main input and output between the Hippocampus and the neocortex/rest of the subcortical areas (notably associational, perirhinal, and papahippocampal). The information coming to the hippocampus from both the poly- and unimodal association cortices, converge in the EC.
- *EC as a whole, therefore, receives highly processed input from every sensory modality, as well as input relating to ongoing cognitive processes, though it should be stressed that, within EC, this information remains at least partially segregated. *
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Architecture of the Entorhinal Cortex A Review of Entorhinal Anatomy in Rodents with Some Comparative Notes
- Layer II cells come in two, chemically defined types, reelin- and calbindin-positive.
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- Fan cells are just the term for stellate cells in the LEC.
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- Connects to the rest of the Hippocampus formation via the perforant path, of which there are multiple layers that connect to different areas. I think the most prominent ones are the connections to the DG and to the CA3:
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- The layer III pathway is known as the temporoammonic pathway (kind of intuitive named. The hippocampus is in the temporal lobe)
- I think this is the “main” output of the EC.
- Neurons in layer II project to the DG and CA3, whereas layer III cells project to CA1 and the subiculum
- The layer III pathway is known as the temporoammonic pathway (kind of intuitive named. The hippocampus is in the temporal lobe)
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- I think this is for place cells/grid cells: https://www.researchgate.net/figure/Proposed-ring-attractor-in-the-superficial-layers-of-the-entorhinal-cortex-Five_fig1_344267483