Connectome

links: reference:

• Neuronal Graphs: A Graph Theory Primer for Microscopic, Functional Networks of Neurons Recorded by Calcium Imaging
• http://www.scholarpedia.org/article/Connectome 11-4-2021

Connectome #

A map of Neural Circuits of the Brain.

• Altered functional and structural brain network organization in autism
  • Reduced short and long-range connectivity within functional systems (i.e., reduced functional integration) and stronger connectivity between functional systems (i.e., reduced functional segregation), particularly in default and higher-order visual regions.
• Graph theoretical analysis of complex networks in the brain
  • A scale-free network is essentially one with some ‘hubs’ with many connections. It has a power-law degree distibution: while random = bell curve.
• Efficiency of Functional Brain Networks and Intellectual Performance
  • We show a strong negative association between the normalized characteristic path length λ of the resting-state brain network and IQ.
  • The brain consists of local, small-world functional connections together with long-distance connections.
  • Most pronounced effects between normalized path length and IQ were found in frontal and parietal regions. (Parieto-Frontal Integration Theory right again)
  • Neuroimaging studies have linked intelligence to the developmental course of specific high-order brain regions:
• Genetics of Brain Fiber Architecture and Intellectual Performance