Casomorphin

2022-02-14 links: reference:

Casomorphin #

• Opioid peptide, divided into β-casomorphin 1-3, and bovine β-casomorphin 1-8.
• β-Casomorphin binds to μ-Opioid Receptor.
• A naturally occurring opioid peptide from cow’s milk, beta-casomorphine-7, is a direct histamine releaser in man
• Autistic children display elevated urine levels of bovine casomorphin-7 immunoreactivity
• A Peptide Found in Schizophrenia and Autism Causes Behavioral Changes in Rats
  • *In a previous study we showed that β-casomorphin-7 (β-CM7) is taken up by brain regions relevant to schizophrenia and autism. The present experiment was designed to find whether β-CM7 has any behavioral or analgesic effects in rats. About 65 seconds after treatment with different doses of β-CM7, rats became restless and ran violently, with teeth chattering and with rapid respiration. Seven minutes later, the rats became inactive with less walking, distancing themselves from the other rat in the same cage, and sitting in, or putting their head against, the corner of the cage. *