Azelaic Acid

2023-04-07:

Azelaic Acid #

• Inhibits Tyrosinase. Antioxidant. Antibacterial. 5-AR inhibitor: Inhibiton of 5 alpha-reductase activity in human skin by zinc and azelaic acid
• Used for acne, rosacea, melasma, and hyperpigmentation.
  • Anti-keratinizing agent: Mechanism of azelaic acid action in acne
• Slows down the prodction of protein? Keratin at least etc. This is a good thing apparently in that it prevents formation of overly tough skin.
• Naturally found on the skin as it’s made by a certain yeast.

Products #

• https://www.stbotanica.com/product/azelaic-acid-alpha-arbutin-hyaluronic-acid-professional-face-serum.html EWG 4 because of phenoxyethanol but it may be safe.
• https://www.ncskin.co.uk/product-page/azelaic-acid-serum 20%! from the UK - will they even ship? EWG 2 - wtf is hydrolyzed sclerotium gum though?
• https://gardenofwisdom.com/products/azelaic-azeloyl
  • 8% is EWG 1 but it has soy-based liposome. 8% also has potassium azeloyl diglycinate, which is the only difference between the 2 on this site (so there’s 3 versions total)
  • https://victoriahealth.com/azelaic-acid-10-serum/
    • Old old 10% formulation is EWG 1 as well besides jojoba protein, phospholipon unknown, and sodium lactate (3). Seems safer than the other one considering it doesn’t have soy tbh but who knows.
  • Leucidal Sf = lactobacillus ferment. A probiotic anti-acne probiotic
• Cos de Baha: $12.5 for 30mL of 10% https://www.yesstyle.com/en/cos-de-baha-az-azelaic-acid-10-serum-30ml/info.html/pid.1103824132. That’s like half the price of GoW too

Just get pharma Aziderm on sites like ADC/DashPCT.

• 10% gel ≈ 20% cream in terms of strength/penetration. Dunno how that compares to stuff liek GoW, then, which is liposomal. ChatGPT says it might even be at least as strong as gel.